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New device could reduce surgical scarring

Researchers at Stanford University have developed a special wound dressing that they report was able to significantly reduce scar tissue caused by incisions.

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Bioengineers identify the cellular mechanisms of traumatic brain injury

Bioengineers at Harvard have identified, for the very first time, the mechanism for diffuse axonal injury and explained why cerebral vasospasm is more common in blast-induced brain injuries than in...

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Mechanical stress can help or hinder wound healing depending on time of...

A new study demonstrates that mechanical forces affect the growth and remodeling of blood vessels during tissue regeneration and wound healing. The forces diminish or enhance the vascularization...

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Molecular probes identify changes in fibronectin that may lead to disease

Fibronectin plays a major role in wound healing and embryonic development. The protein, which is located in the extracellular matrix of cells, has also been linked to pathological conditions including...

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To make old skin cells act young again, boost their surroundings, scientists...

As we get older, the trillions of cells in our body do too. And like us, they become less resilient and able to weather the stress of everyday life. Our skin especially tells the tale of what's...

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Team creates cells that line blood vessels

In a scientific first, Harvard Stem Cell Institute scientists have successfully grown the cells that line the blood vessels—called vascular endothelial cells—from human induced pluripotent stem cells...

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Understanding the mechanics of cells to provide new medical insights

University of Southampton researchers are at the forefront of research into mechanobiology, an emerging field of science combining biology and engineering, which investigates the influence of...

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A storm in our veins

Suppose you're hiking through the forest on a sunny afternoon as a light breeze passes through the trees, gently grazing your skin. Suddenly the sky opens up and a rainstorm ensues. The trees keep you...

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Baby hearts need rhythm to develop correctly

(Medical Xpress)—To develop correctly, baby hearts need rhythm...even before they have blood to pump.

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Scar findings could lead to new therapies

Researchers at the Stanford University School of Medicine report that they have identified the molecular pathway through which physical force contributes to scarring in mice.

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How immune cells move against invaders

UCSF scientists have discovered the unexpected way in which a key cell of the immune system prepares for battle. The finding, they said, offers insight into the processes that take place within these...

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Helping Hands reaches out to patients with cerebral palsy

With the aid of multiple force sensors and a digital dinosaur, a team of Rice University seniors known as Helping Hands hopes to restore strength and flexibility to the hands and wrists of children...

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Lungs respond to hospital ventilator as if it were an infection

When hospital patients need assistance breathing and are placed on a mechanical ventilator for days at a time, their lungs react to the pressure generated by the ventilator with an out-of-control...

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Secrets of gentle touch revealed

Stroke the soft body of a newborn fruit fly larva ever-so-gently with a freshly plucked eyelash, and it will respond to the tickle by altering its movement—an observation that has helped scientists at...

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Researcher provides insight into osteoarthritis

A researcher at The Feinstein Institute for Medical Research has discovered additional mechanical properties of articular cartilage, a protective cartilage on the ends of bones that wears down over...

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Study reveals target for drug development for chronic jaw pain disorder

Temporomandibular joint disorder (TMJD) is the most common form of oral or facial pain, affecting over 10 million Americans. The chronic disorder can cause severe pain often associated with chewing or...

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Researchers discover reversible mechanism that increases muscle elasticity

How does yoga improve your flexibility? In the Mar 13 cover story of Cell, Columbia University biological sciences professor Julio Fernandez and team report the discovery of a new form of mechanical...

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Researchers show how cancer cells may respond to mechanical force

The push and pull of physical force can cause profound changes in the behavior of a cell. Two studies from researchers working at the UNC Lineberger Comprehensive Cancer Center reveal how cells respond...

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Xenon gas protects the brain after head injury

Treatment with xenon gas after a head injury reduces the extent of brain damage, according to a study in mice.

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Atomic-level view provides new insight into translation of touch into nerve...

Whether stubbing a toe or stroking a cat, the sensation of touch starts out as a mechanical force that is then transformed into an electrical signal conveying pain or other sensations. Tiny channels in...

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Forcing wounds to close

A collaborative study led by scientists from the Mechanobiology Institute (MBI) at the National University of Singapore (NUS) has revealed the mechanical forces that drive epithelial wound healing in...

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Cancer treatment models get real

Researchers at Rice University and University of Texas MD Anderson Cancer Center have developed a way to mimic the conditions under which cancer tumors grow in bones.

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Asthma cells scramble like 'there's a fire drill'

In people with asthma, the cells that line the airways in the lungs are unusually shaped and "scramble around like there's a fire drill going on." But according to a study at the Harvard T.H. Chan...

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Muscles on-a-chip provide insight into cardiac stem cell therapies

Stem cell-derived heart muscle cells may fail to effectively replace damaged cardiac tissue because they don't contract strongly enough, according to a study in The Journal of Cell Biology. The study,...

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Demystifying mechanotransduction ion channels

As blood flows through our vessels, the cells that constitute these vessels responds to the shear stress of blood flow to ensure normal circulation. This process of converting a mechanical force into a...

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T cells use 'handshakes' to sort friends from foes

T cells, the security guards of the immune system, use a kind of mechanical "handshake" to test whether a cell they encounter is a friend or foe, a new study finds.

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